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the rate of biopsy-confirmed acute graft rejection in the seronegative group was 52 percent among placebo recipients and 26 percent among valacyclovir recipients (P=0001)!
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instead of having equal probabilities, the values have different probabilities, let x 1 have probability p 1, x 2 have probability p 2, , x N have probability p N!
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49 (48%) patients experienced a Sjo 2 < 50%, and the mean total duration of Sjo 2 < 50% was 44 (sd 97) min?
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So even though valacyclovir hasn't actually been studied in pregnant women, almost certainly it is entirely safe.